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KMID : 0191120120270070827
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Journal of Korean Medical Science
2012 Volume.27 No. 7 p.827 ~ p.829
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Suspected Anaphylactic Reaction Associated with Microemulsion Propofol during Anesthesia Induction
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Lee Se-Jin
Kim Soon-Im
Jung Bo-Il
Lee Su-Myung
Kim Mun-Gyu
Park Sun-Young
Kim Sang-Ho
Ok Si-Young
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Abstract
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Although rare, intraoperative anaphylaxis can lead to significant morbidity and mortality. Aquafol® (Daewon Pharmaceutical Co. Ltd., Seoul, Korea), a microemulsion propofol, was developed to eliminate lipid solvent-related adverse events, and was used in clinical anesthesia since 2009 with little data about severe side effects such as anaphylaxis. A healthy 16-yr-old male patient who had past medical history with two previous operations of no complications developed cardiovascular shock with generalized erythema following administration of microemulsion propofol during anesthesia induction. Intravenous injection of epinephrine and steroid rescued him. He remained in a stable state without any problems postoperatively and was discharged. Clinicians should consider this rare but serious complication during induction of anesthesia with propofol.
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KEYWORD
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Anaphylactic Reaction, Anesthetics, Aquafol, Complications, Microemulsion Propofol
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